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Combi𝑭𝒍𝒂𝒔𝒉 Torrent

Large-Scale Flash Purification

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CombiFlash Torrent system
CombiFlash Torrent system
Large 8.6 kg column

Versatile Large-Scale Flash Purification

CombiFlash Torrent® systems from Teledyne ISCO provides the ease of use and high reliability of our CombiFlash and RediSep® product lines in a large, development-scale platform. Packed with time-saving features and controlled by our innovative PeakTrak® software, the CombiFlash Torrent accommodates a broad range of injection, detection, and collection requirements. The CombiFlash Torrent can perform either normal phase or reverse phase purifications.

Safety

Patented active solvent sensing technology monitors solvent supply and waste levels for true walk-away automation. Pressure and vapor sensors ensure safe operation by stopping the purification when pressure increases or a leak is detected. Fully grounded tubing allows safe operation at high flow rates. Optional air purging of the column after use simplifies disposal.

Versatility

Tailor a system to meet your needs with a variety of sample introduction and fraction handling configurations.

Highly Programmable and Easy to Use

Teledyne ISCO’s powerful yet intuitive PeakTrak software—the industry standard in flash chromatography—lets you quickly access and edit every method parameter from one screen.

​​​Download Our
Flash Guide​​FREE Download
Solvent Miscibility Chart​​


Run​ up to 1 L/min​ binary gradient system

​​​Load up to 300 grams in a single purification run


Normal​​ phase and reverse ​​phase purifications

Flexible for a wide variety of normal phase and reverse phase purifications, including natural products, peptides and oligonucleotides.​

Patented active level sensing

Active level sensing ensures adequate solvent for purifications and prevents waste overflows.

Evaporative Light Scattering Detector (ELSD)

ELSD has self-contained flow splitter pump for minimal sample loss.


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Options and Accessories

Fraction collection

Fraction collection

Daisy-chain up to four Foxy® R2 fraction collectors for hundreds of fractions. Choose from a variety of collection containers.

peristaltic pump

Pair with PeriXus®

Pump large volumes of liquid sample using external PeriXus orperistaltic pump from containers or an open-top cartridge.

reciprocating pump

Pair with ReaXus®

Pump large volumes of liquid sample using external ReaXus reciprocating pumps from containers or an open-top cartridge.

Flash Chromatography Columns

Flash Chromatography Columns

Easy, error-free setups for large purifications. Load methods from RFID technology on RediSep columns for faster setups and fewer errors.

Specifications

Sample size:

0.5 to 300 grams

RediSep column sizes:

80 grams to 8.6 kilograms

Flow rate:

50 – 1000 mL/min

Maximum pressure:

100 psi (6.89 bar)

Detection:

200 – 400 nm (200 – 800 nm optional) with single, dual, or All-wavelength collection. Accepts external detector input.

Gradient:

Binary, high pressure solvent mixing with linear, step, or isocratic capability. Two solvent inlets.

Gradient accuracy:

<2% full scale from 0.2 to 1.0 liter/min.

Sample injection:

Automated injection with options of solid load cartridges, liquid load, or direct injection.

Controller:

10.4 in (26.7 cm) touchscreen

Software:

On-screen method development and control with PeakTrak software.

Fraction collection:

Up to four fraction collectors, fractionation valve, or manual collection.

Solvent management:

Patented, active level sensing for inlet and waste containers.

Module Dimensions:

(W x D x H) 18.5 x 17.9 x 28.1 in (47 x 43.5 x 71.4 cm)

Module weight:

65 lbs (29.5 kg)

Operating voltage:

100 VAC 50 Hz, 117 VAC 60 Hz, 234 VAC 50 Hz

Safety and sample security:

• Static-dissipative tubing throughout

• Vapor sensor for internal leak detection

• Overpressure sensor

• Active solvent and waste level sensing

• Audible alarm when user intervention is required

Certification:

CE

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